What is homology?
Homology is the similarity in structure, physiology or development of organisms based on their evolution from a common ancestor [1]. Homologs have a high degree of sequence similarity [2].
Finding the gene homologs of NTRK1
HomoloGene was used to identify the homologous genes of NTRK1. The six species highlighted in this homology analysis are: chimpanzee, chicken, cattle, mouse, zebra fish and Arabidopsis.
NTRK1 Gene Reference Pages
NTRK1 Gene Homologs Reference Pages
Pan troglodytes - Chimpanzee
Identity (%): 99.6 |
Discussion
Pairwise alignment and blast scores were used to determine the percent identity of each gene homolog. The higher the percent identity the greater the similarities between gene sequences. The chimpanzee has the highest percent identity, which makes sense because chimpanzees are humans' closest evolutionary relatives.
References
[1] "homology." Encyclopædia Britannica. Encyclopædia Britannica Online. Encyclopædia Britannica Inc., 2013. Web. 20 Feb. 2013. <http://www.britannica.com/EBchecked/topic/270557/homology>.
[2] "Gene Similarity: Some Definitions." Gene Similarity: Some Definitions. J. H. Jackson Laboratory, 08 Apr. 1999. Web. 20 Feb. 2013.
[2] "Gene Similarity: Some Definitions." Gene Similarity: Some Definitions. J. H. Jackson Laboratory, 08 Apr. 1999. Web. 20 Feb. 2013.